SMB

DNA cleavage and opening reactions of human topoisomerase IIα are regulated via Mg2+-mediated dynamic bending of gate-DNA

Sanghwa Lee, Seung-Ryoung Jung, Kang Heo, Jo Ann W Byl, Joseph E Deweese, Neil Osheroff, Sungchul Hohng

Proceedings of the National Academy of Sciences

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https://doi.org/10.1073/pnas.1115704109