Professor Sungchul Hohng

Sungchul Hohng

Professor, Department of Physics and Astronomy

Seoul National University

Single Molecule Biophysics Lab

shohng at snu.ac.kr

Professional Summary

Research in single-molecule biophysics investigates molecular interactions involved in transcription regulation and genome maintenance. Single-molecule fluorescence imaging and molecular manipulation help reveal the mechanisms underlying these processes, with potential applications in molecular diagnostics.

Academic Qualifications and Career

  1. ProfessorDepartment of Physics and Astronomy, Seoul National University
  2. Postdoctoral Research AssociateUniversity of Illinois at Urbana-Champaign (UIUC)
  3. Postdoctoral Research AssociateSeoul National University

Honors and Awards

  1. Regular MemberKorean Academy of Science and Technology
  2. Academic AwardKorean Physical Society
  3. Scholarly Research AwardSeoul National University
  4. Outstanding ScientistMinistry of Science and Technology

Selected Publications

  1. Human RNA polymerase III termination favors decomposition over facilitated recycling Han, S., Wang, Q., Song, E., Kang, C., Xu, Y., & Hohng, S. Nature Communications (2026)
  2. Ultrafast and specific miRNA quantification via single-molecule fluorescence quenching kinetics Kim, J., & Hohng, S. Communications Biology 9, 432 (2026)
  3. Fast, sensitive, and specific multiplexed single-molecule detection of circulating tumor DNA Shin, S., Han, S., Kim, J., Shin, Y., Song, J.-J., & Hohng, S. Biosensors and Bioelectronics 242, 115694 (2023)
  4. Quantification of purified endogenous miRNAs with high sensitivity and specificity Shin, S., Jung, Y., Uhm, H., Song, M., Son, S., Goo, J., Jeong, C., Song, J.-J., Kim, V. N., & Hohng, S. Nature Communications 11, 6033 (2020)